DPCstruct | MC17356

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)190 ± 51 aa
Standard deviation of domain lengths51.41
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score84.73
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)45.34
Pfam Score71.72
Assigned Pfam label(s) CL0111- CL0264- CL0492- CL0072- PF04487

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I7M9C4 75-318 PKKHLKRINAPKSWMLNKLGGIWATRPSQGPHKLRESLPLSVLLKERLNYALNGRDVTLILNDKEQNVFVDGKVRRDKGYPTGLMDV…
A0A7J2I2R1 6-201 NAGKHSIRDSVPLGYFLKYLGFANTTREAKKLLLLTDVLIDGRKVKDVKCPVGFMDSIVVGQKAFRCLFGNKGRIIFIEVNDSDKKI…
A0A226NAC6 1-138 None
A0A3M0JB68 349-595 None
A0A2G5DC30 68-286 None
A0A2R6FHV0 16-249 None
A0A0B2NY19 2-116 None
A0A1Q9E4M4 4-146 None
A0A1E4SSI4 19-263 None
A0A4Y7LAX9 1-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.