DPCstruct | MC17350

Metacluster Properties and Pfam Annotations

Number of structural domains1345
Mean domain length (aa)423 ± 103 aa
Standard deviation of domain lengths102.53
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score75.64
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)12.74
Pfam Score32.90
Assigned Pfam label(s) CL0110- PF14291- PF12017- PF06507- PF10683

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R1RNE8 20-248 PENIGAYISIDETAFSNGDLYTILTNKKAKGKKGALVLMVKGTKAETVTKILHKIPLKQRKKVKEVTLDMAGNMGLIVKKSFPSATL…
A0A6A4JER2 61-495 SNNLKRAGMQSKIEDFSIKKLTPAAKKNIDGALLNMFTRDYQPFSVVEDKGFKKFVKTLNPSYTLPSRKKISSTLIPSRYEEIKLEL…
A0A815FTQ9 72-352 None
A0A3P8N8K8 21-327 None
W4H349 71-356 None
W4GG46 2-288 None
Q27395 33-540 None
A0A5A9N9P4 2-344 None
A0A4C1UKY6 17-398 None
A0A4C1UCM7 479-834 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.