DPCstruct | MC17341

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)164 ± 26 aa
Standard deviation of domain lengths26.31
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score72.65
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.66
Pfam Score91.98
Assigned Pfam label(s) CL0126- PF15309- PF17730- PF01562- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0E3NWU4 64-217 YPSREAPVYEGIEFDKNSLRFSEIFSDFDTVTANPDAFRKAAEDGTIELYLRGRAFELEFDVAETFTPKVIMENESGFYTEETAPIS…
A0A2G8K3E4 22-191 DKLIQQFGHYELVVPSLVNHRGDFLSYDIINSRKRTRRHLDTHKEPLADKTIHYSVQAYGTQFHMNLTLNTKLISPHFVVEREDRTG…
H3B578 1-127 None
A0A5E4QDE8 32-188 None
A0A6J3EK86 304-432 None
A0A6I9PWJ2 3-162 None
A0A2I3M3V3 26-186 None
F7EP17 17-190 None
A0A523EFS2 35-204 None
A0A1I8IGK8 182-364 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.