DPCstruct | MC17335

Metacluster Properties and Pfam Annotations

Number of structural domains401
Mean domain length (aa)111 ± 15 aa
Standard deviation of domain lengths14.84
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.55
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.95
Pfam Score96.92
Assigned Pfam label(s) CL0023- CL0213- CL0126- CL0550- CL0168

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3AXC3 28-135 None
H3AXC4 5-114 None
A0A7M5VCD7 217-333 None
K8F6W9 70-179 None
A0A7M5VF05 820-947 None
A0A498P146 10-112 None
V4BVU6 21-167 None
A0A835RNH6 408-518 None
A0A3B4ASH8 2-156 None
A0A4W6FU82 88-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.