DPCstruct | MC17335

Metacluster Properties and Pfam Annotations

Number of structural domains401
Mean domain length (aa)111 ± 15 aa
Standard deviation of domain lengths14.84
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.55
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)20.95
Pfam Score96.92
Assigned Pfam label(s) CL0023- CL0213- CL0126- CL0550- CL0168

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A674F7F5 70-172 YSCVQEHETISSIICEGSDSQLLCDRGEIHIQRANYGRRQHDVCSIGRPDNQLKNTNCLSQSSTSTMSERCDGERQCIVKVSNSVFG…
A0A2G8JVD4 164-287 CSFPVVKLPTKSLVCEGDDYVISCKVNQTIKIIYASYGFQYNDSEARDQCDDFRNSLFLNLDGVRCDPNSTLKASAVCNGLMACTIS…
A0A6P8HGT5 524-622 None
A0A6P8HSC4 27-134 None
A0A6P8IAK3 1111-1221 None
A0A069DN36 19-130 None
A0A1I8HY42 99-212 None
A0A6P4EYU9 14-130 None
A0A069DV34 183-279 None
A0A7M5V162 21-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.