DPCstruct | MC1731

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)138 ± 12 aa
Standard deviation of domain lengths11.84
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score85.11
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)34.49
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2S5E2 12-150 RPEHREKFLPILQHAFYDDLRFCLYAITKEEEEKALETCARELLCLCLEWPLRGLFLETAWKVLKYVEVRYLSVLLYQIFETKRKWK…
A0A4Y2KD56 1-137 MPGERRILLPHLGHLCKADDLRFCLYVLTKEEQEKVLESSCIEVLQLHMNWPLARDFLKIAEKTWNFLIEYSFCIVLENLLDRRDRT…
A0A4Y2G5H7 142-272 None
A0A4Y2LWP2 26-179 None
A0A4Y2NS08 2-136 None
A0A4Y2NA22 275-428 None
A0A4Y2RYG5 250-370 None
A0A4Y2RUM8 1-125 None
A0A4Y2RPB0 85-229 None
A0A4Y2QPF5 63-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.