DPCstruct | MC17299

Metacluster Properties and Pfam Annotations

Number of structural domains174
Mean domain length (aa)140 ± 37 aa
Standard deviation of domain lengths36.71
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score91.99
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.29
Pfam Score89.06
Assigned Pfam label(s) CL0159- CL0635

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A661MDM2 151-359 None
A0A7V9FMB8 28-156 None
A0A2D9HB58 218-413 None
A0A2W5NAP1 2-85 None
A0A7C5BTN6 265-431 None
A0A7X7ADT1 184-352 None
A0A537Y576 150-351 None
A0A7X6U8B3 2-107 None
A0A354P390 287-460 None
A0A354PGV8 1-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.