DPCstruct | MC17274

Metacluster Properties and Pfam Annotations

Number of structural domains411
Mean domain length (aa)340 ± 68 aa
Standard deviation of domain lengths67.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)11.82
Pfam Score89.65
Assigned Pfam label(s) CL0052- PF00305- CL0649- CL0059- CL0176

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812WXB6 187-547 None
A0A6P7GL89 8-272 None
A0A4C1Y4A2 31-467 None
A0A653CWT2 2-231 None
A0A4Y2E8Q9 13-228 None
A0A1S4G5Q2 8-308 None
R7VGJ8 15-398 None
R7UWX7 44-480 None
A0A3F2ZEC0 32-407 None
E2AN88 1-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.