DPCstruct | MC17274

Metacluster Properties and Pfam Annotations

Number of structural domains411
Mean domain length (aa)340 ± 68 aa
Standard deviation of domain lengths67.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)11.82
Pfam Score89.65
Assigned Pfam label(s) CL0052- PF00305- CL0649- CL0059- CL0176

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A4J5Z4 227-582 None
A0A7D0TEI3 275-618 None
A0A7R8V590 2-286 None
A0A6A4X187 55-502 None
A0A813LXA6 7-280 None
A0A221I0I8 7-211 None
A0A7R9GC88 97-521 None
A0A5D2MN61 16-375 None
A0A5E4MTS4 22-335 None
A0A7S0ZRI5 26-437 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.