DPCstruct | MC17274

Metacluster Properties and Pfam Annotations

Number of structural domains411
Mean domain length (aa)340 ± 68 aa
Standard deviation of domain lengths67.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)11.82
Pfam Score89.65
Assigned Pfam label(s) CL0052- PF00305- CL0649- CL0059- CL0176

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1B0GFD7 10-234 None
A0A0L0CQE6 3-218 None
A0A6P4JHD4 1-272 None
A0A226DVI6 156-492 None
A0A0E0E418 34-453 None
A0A7S0FCG7 2-225 None
A0A4S2K133 5-278 None
A0A1D1VLU9 4-353 None
A0A4Y2FTS5 5-218 None
A0A2R7X0R1 5-298 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.