DPCstruct | MC17274

Metacluster Properties and Pfam Annotations

Number of structural domains411
Mean domain length (aa)340 ± 68 aa
Standard deviation of domain lengths67.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)11.82
Pfam Score89.65
Assigned Pfam label(s) CL0052- PF00305- CL0649- CL0059- CL0176

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834JSI0 2-311 None
A0A164PJY8 757-1145 None
A0A1J1J8L0 22-280 None
A0A1A9ZB31 9-264 None
A0A7R9E0J9 51-331 None
U4UKK2 3-369 None
A0A1I8M3R9 8-358 None
B4JDC3 99-395 None
A0A6P4ITJ6 177-424 None
A0A182T3G3 5-242 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.