DPCstruct | MC17274

Metacluster Properties and Pfam Annotations

Number of structural domains411
Mean domain length (aa)340 ± 68 aa
Standard deviation of domain lengths67.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)11.82
Pfam Score89.65
Assigned Pfam label(s) CL0052- PF00305- CL0649- CL0059- CL0176

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182Q6H0 82-421 None
A0A7R8ZCG5 2-232 None
A0A7J6G8E9 15-459 None
A0A6J1Q570 7-579 None
A0A6J1PZM0 39-424 None
A0A2A3ETM1 108-432 None
A0A6J1PQA1 6-230 None
A0A6J1PL00 8-440 None
A0A6J1PIB8 35-442 None
A0A2R7WE70 34-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.