DPCstruct | MC17258

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)133 ± 3 aa
Standard deviation of domain lengths3.01
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score90.41
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)46.24
Pfam Score96.15
Assigned Pfam label(s) CL0179- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446J2N2 1-132 MDIPHALFEEKLEAMKATKGVDNDTDLTANDLRELVGQYKNVYVEAKGEQFPSDPKRQLQLAVLAVFDSWDSPRANKYRSINQITGL…
A0A452Z2X0 95-225 MDIPHALFEEKLEAMKAAKGVDNDTDLTANDLRELVGQYKNVYVEAKGEQFPSDPKRQLQLAVLAVFDSWDSPRANKYRSINQITGL…
A0A1Z1WQJ5 141-275 None
A0A380FM77 43-178 None
H2K6P8 1-132 None
A0A7C4NU46 678-808 None
A0A2P9IQ49 141-273 None
W7TQY3 254-383 None
A0A2U1QDL6 273-408 None
W7C1N9 147-282 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.