DPCstruct | MC17255

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)158 ± 38 aa
Standard deviation of domain lengths37.52
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score84.88
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)29.86
Pfam Score100.00
Assigned Pfam label(s) CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8C4U0 3-124 PIWKQQARPGDGPVIWDYHVVLLHVSSGGQSFIYDLDTVLPFPCAFDAYVEDAFKSDEDIHPQFRRKFRVIRADSYLKNFASDRSHM…
A0A452Z0J9 1-154 MIIQLQCEENVHLLCKELIRAGLADPAGNDLYAVFVSNEEKKIPLWYQKASRTNDGFVLWDYHVICIQSRRNKGDVLDLVWDLDSSL…
A0A7S1QWZ5 40-243 None
T1ESK0 174-263 None
A0A109FMB3 1-151 None
A0A2G2XAD6 349-520 None
A0A284QUW2 9-141 None
A0A146H6K5 283-441 None
A0A2G3CDQ6 269-438 None
A0A7R9PWG4 140-319 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.