DPCstruct | MC1725

Metacluster Properties and Pfam Annotations

Number of structural domains99
Mean domain length (aa)191 ± 47 aa
Standard deviation of domain lengths46.52
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score80.43
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.62
Pfam Score64.10
Assigned Pfam label(s) PF08399- CL0165- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C9LYA1 22-189 MEDLLDEKKKAVMRLKAAAQNSMKNYGAYTNTIDFNDVKYYNAKKVVIETDLENMDNDTKDAIKETINYLPTEPMWSFKKEEMRPKL…
A0A6G1Q2V3 11-203 VRVEEIDGLRLVKRLAEDMEEMFHKKAQAMKRLVEAAEEAHLQHEEDPNLQYEYFNAVLINEVDEEGNSVELGGEFILQPNDHFNNL…
A0A6A4VHY1 36-176 None
A0A1X6PH68 14-256 None
A0A668AFN1 78-275 None
A0A183WNT4 8-141 None
A0A6V7H9I7 2-283 None
A0A7D9LBN2 36-200 None
A0A7X7DGK8 529-712 None
A0A7S3LUJ6 57-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.