DPCstruct | MC17246

Metacluster Properties and Pfam Annotations

Number of structural domains89
Mean domain length (aa)139 ± 23 aa
Standard deviation of domain lengths23.18
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.20
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.39
Pfam Score83.25
Assigned Pfam label(s) CL0123- CL0040- CL0125- CL0383

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376P644 20-180 TGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVIDITNEATLPKRATITLRRSKLDRLIGHYIADEQVTDIL…
A0A452YQX1 3-134 MFSEYCENKFEVEPVEVVSHDGSTAIYPDLSCYKMEVSLSDIVGPIGISLDETQVISLLNKMQLQADLCSSNREPCISVSVPPTRSD…
K2D7H2 519-652 None
A0A2R6CSQ8 711-845 None
A0A837Q1U2 25-160 None
A0A401FKK8 135-291 None
A0A7Y3PI76 1-110 None
A0A7V6GNP8 391-493 None
A0A3Q0JHG0 69-212 None
A0A831V2C2 236-392 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.