DPCstruct | MC17204

Metacluster Properties and Pfam Annotations

Number of structural domains853
Mean domain length (aa)82 ± 15 aa
Standard deviation of domain lengths14.50
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.19
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.43
Pfam Score99.14
Assigned Pfam label(s) CL0063- PF11409- PF11979- PF09311- PF12767

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3HCR4 222-311 None
H3HCT3 844-927 None
H3HDK6 284-356 None
A0A6P6DQ10 483-561 None
G5AUI1 680-772 None
W2Y4Z0 264-355 None
W2Y5I6 102-191 None
A0A1E7EUW3 9-97 None
W7TC83 196-276 None
A0A210PMU2 37-103 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.