DPCstruct | MC17198

Metacluster Properties and Pfam Annotations

Number of structural domains247
Mean domain length (aa)227 ± 36 aa
Standard deviation of domain lengths35.51
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.28
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.26
Pfam Score93.94
Assigned Pfam label(s) PF01124- CL0172- CL0292- CL0342

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A482ZKS7 2-196 DIGVLYKVTIFWVIFYITPGPVWVSVMEATRKLSFTGIWQFFIRVFLPVNASVQFLQALICAIFVEFVATIFSQIGLLFYILGGSYI…
A0A662PL49 77-320 DELVEEDGAYGSEGSDGMGCLSFLAITVAALVDSINPCSMAILFFLLAGLLLLRKRKKALRVGLAFTLSVFVANLLFGFGILSAVVL…
A0A171JVJ2 14-211 None
A0A1G2VLK1 4-231 None
A0A2E2YND2 1-244 None
B9XS93 1-221 None
A0A1W1B8S5 1-251 None
A0A656HKX2 94-292 None
A0A0G1H343 1-241 None
A0A6V8ENU0 81-347 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.