DPCstruct | MC17145

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)265 ± 55 aa
Standard deviation of domain lengths54.74
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score70.98
Mean fraction of residues predicted as intrinsically disordered0.78
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)25.45
Pfam Score86.84
Assigned Pfam label(s) PF19252- PF03343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A250XJM3 27-270 IEETNRLRISLGLKPLNMEAPQKQSAVDVKKQEQARKEAEQERLAADLRARIEAHKSARQQQSFLAVKGLGEADEDDDMASWVERSR…
A0A0T6B9L9 98-353 IDETNKLRAKLGLKPLELSTDERKSDGKKKDEWGEFYHKPAANLSEKKEQEKIKAKLSEHREKRQIMNKLVKTKTLGESDSEDDVST…
A0A7S3ZNY7 2-403 None
A0A453DHS1 6-222 None
A0A6I9YMW1 2-196 None
B5VSI6 2-209 None
A0A0M3IKG4 2-244 None
A0A061F9H8 120-377 None
A0A4Y7IKL1 69-270 None
A0A6J2K301 16-301 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.