DPCstruct | MC17112

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)75 ± 11 aa
Standard deviation of domain lengths11.45
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.71
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)39.64
Pfam Score100.00
Assigned Pfam label(s) PF01220

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C6DAW3 2-59 HILVVNGPNMNMLGIRQPEIYGHETYEDLKALIRAEADRLGASVSFFQSNHEGALVDE
Q9X658 42-109 MNGPNLGILGRRQPEIYGTDTLADIEGRVAEEVTETRLEIEAFQHDGEAEMLRTIQADHDTACAIINP
A0A3R8PKM2 2-59 None
A0A257XWY0 19-92 None
M9ME92 16-86 None
A0A4S2UDJ7 9-62 None
A0A4Q3H1B9 3-67 None
W8YZ60 186-255 None
A0A0G1YWI4 2-74 None
A0A839SR35 1-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.