DPCstruct | MC17111

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)194 ± 29 aa
Standard deviation of domain lengths29.34
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.96
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)20.64
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1TBJ4 42-255 AAATQPGEMVRDFAPGVQVVLGKRVILTGSVIMDQGPVDGLEVLACLASGKTHEAIVRLAAPDGHTARAAFTAALGLEKEGVPAPES…
A0A2A2RXD4 2-178 KLNMTNGPIEYLLVTTAGKTHESLLTTDIEPQHLQVAMLLLGAKGMQAAPLTNAPAGGPITQALGGRNPPLPGDAVSVEVSWKQGGR…
A0A4P5Y435 24-218 None
A0A7X7J3X9 39-245 None
A0A286RE36 176-366 None
A0A851GR69 113-291 None
A0A7V2UWM5 86-289 None
A0A800M9Z2 31-232 None
A0A2A4RRL5 21-222 None
A0A353F7E8 1-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.