DPCstruct | MC17108

Metacluster Properties and Pfam Annotations

Number of structural domains1177
Mean domain length (aa)145 ± 39 aa
Standard deviation of domain lengths39.02
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score75.22
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.36
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.01
Pfam Score97.81
Assigned Pfam label(s) PF07486- CL0125- CL0187- CL0244- CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N7YZY6 13-116 DLKFFVMPVDADVSDIAKKFGISEKRLMKYNELESSKLAKNDIIFLEGKNSSGNKDTYKAGIGETMHDIAQKFGIKEKKLYAKNRME…
A0A415Y5M9 3-134 IIVYTVNKGDTLHNIAEKFGSSVNAIARANGIVAPFKIYPDQSLRIPVFEEPNFITYTVQPGDTLYSLAEYFGTTVGELANANELED…
A0A2B7XFV4 213-387 None
A0A4S8MPN6 11-135 None
A0A1L9VV34 75-196 None
A0A1L9V3P3 88-209 None
A0A4S9JTH6 228-476 None
A0A496Q1K3 87-223 None
A0A3L7PQY3 143-289 None
A0A167LKF7 33-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.