DPCstruct | MC17069

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)684 ± 94 aa
Standard deviation of domain lengths93.57
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.67
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.04
Pfam Score72.63
Assigned Pfam label(s) PF10162- CL0268- PF13330- CL0159- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q54XG9 575-1301 SPSSNITLPEGKKVLISPCSISQTQVYKWIKVPSTSELIFADSPMDFHVKDIYVEGKFIMGTTKCRYNSKINIIFHGEKTLSDTISQ…
A0A261GRZ8 194-912 LPLWSDAETWMEGTPPEFGSEVVIPAGATVVMDNANASSVIRVSGILTTPLNRDFSLNANEVHILSGGLLELGRADAPYLGKGTVTL…
A0A183MTW7 8-537 None
A0A813VGQ8 59-829 None
A0A7V8ZH07 301-981 None
A0A2D6E5T0 260-853 None
A0A4V3HH68 66-850 None
A0A7S1VAV1 243-801 None
A0A7S1V3F9 4-696 None
A0A858RNI4 25-663 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.