DPCstruct | MC17046

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)168 ± 18 aa
Standard deviation of domain lengths17.93
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score72.31
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)57.18
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446LXV7 101-253 ERVSQETADGMGANCMHGRLNCGADCVWQASLVVSFGVWCIRWVLDQSLAESRPELWGKYTYVLNRLQGILDPAFCKPRKPVSGCSC…
B8AQ12 1-143 MSLLPKCGDDCVWQAPLIVSFGVWCIRQILNLCLVESRPELWGKYTYVLNRLQGILDPAFSKPRKPMKGCVCLQKVAKPISGTFTTA…
A0A0P0X2N3 431-599 None
A0A1Z5RNP0 504-639 None
A0A0A8YW87 46-203 None
A0A059A112 1086-1270 None
A0A5N6Q5C9 951-1113 None
A0A5P1F1X4 506-657 None
A0A6G1BQX2 68-240 None
A0A7S5GBN6 792-983 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.