DPCstruct | MC17045

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)385 ± 84 aa
Standard deviation of domain lengths84.28
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score74.14
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)26.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6L7Z2Z1 9-327 GRGWDRGSLYYGHRHARRLPKEAQPPFYKKVFAFIFGPEEPRPTQVQKDRGFLRLIRARKGVLTTAELVEHTALTLDDAREEMGRLT…
B8AJ12 12-396 TIGDVSEEGEVLYVFPKDYRAKLAGKSFRMKVEPLIDKTKEVGAYLVRVSFGTALIASIVLVYTTIIAIISSSSDEDNRGRRRRSYD…
A0A388KS96 316-764 None
A0A7S2HYV7 3-279 None
A0A7S2N0H0 1-327 None
A0A086CHV3 47-415 None
A0A7S1D9D0 89-382 None
A0A812I2X9 61-492 None
A0A2E5HNR3 15-482 None
A0A287U353 18-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.