DPCstruct | MC17004

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)468 ± 58 aa
Standard deviation of domain lengths57.84
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score71.52
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A225X7F4 1-317 MPNIKKTVSALVSAFNVNNYARRIIDTNFSVQRRDKRDCLIVSFDKGMDDYQCKRYLSDIKRSIICEFYDVEKGNDKEILNTAELIF…
M9WUU1 1-411 MTSLDFVKELVNAFNVSNYGSKVNTNFVVEGDNIVVKFNCGRRSAKRYLSQMARDLVREYYSDEFVACHVFDLESFPFHFDKKWLKY…
A0A1A9VJW7 63-503 None
A0A060Q1L1 1-497 None
Q5GRL5 20-577 None
Q0RAH9 1-488 None
A0A8A5WA08 1-507 None
A0A7G5CCF5 1-462 None
A0A7G5CAK4 1-503 None
A0A6I5SX41 1-494 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.