DPCstruct | MC16991

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)94 ± 6 aa
Standard deviation of domain lengths5.87
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score94.94
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)46.96
Pfam Score100.00
Assigned Pfam label(s) CL0044

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4WUE4 79-176 MAWGIKRISNDDLRQRFVDATVEQARVLGVTLPDPGLTWNKARGHYDFSPLDWSEFKRVLDGHGPCNRERLATRKRAHEEGEWVREA…
A0A1Y3Q3X7 19-119 KWRIKCDTNDDLREAWLDKIVPLLSSLGYTIHDPLLKKDEHTGRWNYTEVDWEEVKRVINGGGPYSAYWKEKVKKSYEETAWIRDVV…
A0A7C4I998 221-318 None
A0A538AHA4 61-150 None
A0A0K2RN87 3-92 None
A0A7W0PTM6 2-83 None
A0A822E4D5 371-470 None
A0A7K2CPF0 10-99 None
S7X115 217-314 None
A0A7W0FSI4 141-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.