DPCstruct | MC16990

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)156 ± 15 aa
Standard deviation of domain lengths15.02
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score86.82
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)25.70
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2I4H0 9-150 GIKKKEIDYCAIYSRVFTKVTNDRTQQIAETGACDKDTIRKIVYYGIKFVNQLKDINSYEGLIAKFQLISWIKEVIGELTPREFMTI…
A0A1Y3Q3G1 10-161 KKNMPDYFTFYNRIYNDALRRASEKLDSSGELDAEDLKRIVFSGVKMIAHLDDELDYGIATLSIHLIHFITDCASKLTPMEFQTIFP…
A0A6N7WN47 164-326 None
A0A173WAA4 9-188 None
D3ANR5 203-371 None
A0A4Z0QMH3 4-154 None
A0A5R8LDG4 1-174 None
F2JQ53 2-154 None
A0A1I4I7Z6 6-172 None
A0A7G8X113 12-178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.