DPCstruct | MC16984

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)101 ± 10 aa
Standard deviation of domain lengths10.33
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score91.56
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)47.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9HKY7 158-260 IHDHVAQGFARYSTDERWHVPHFEKMLYDQAQLAVAYSAAYLATKDEFYADIVRDILLYVSRDLSDKSGGFYSAEDADSYPSHDAKS…
E2B587 273-379 IHDHVGQGFSRYSVDGEWHVPHFEKMLYDQAQIIQAYADAYVITKDSFYSDIVDDIAKYVERDLRHKEGGFYSAEDADSLPESKSSA…
A0A5N4D5N7 902-1003 None
A0A451AGY9 1-79 None
A0A6G3VRR7 1-89 None
A0A017TIA1 589-695 None
S4RUA8 155-257 None
A0A0D8XUJ6 193-303 None
A0A3P6R406 151-260 None
A0A7J5B9H3 125-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.