DPCstruct | MC16979

Metacluster Properties and Pfam Annotations

Number of structural domains701
Mean domain length (aa)88 ± 16 aa
Standard deviation of domain lengths15.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)17.62
Pfam Score90.47
Assigned Pfam label(s) PF20417- PF06365- PF20660- PF21166- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7KSG5 490-576 None
H2AWI8 30-100 None
F4PLG1 679-768 None
A0A133VRU5 17-80 None
A0A0D3CZB6 1-95 None
A0A164K189 25-97 None
Q4UA02 16-109 None
A0A819U8J0 103-188 None
A0A819ZN18 2-76 None
A0A518CPL3 114-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.