DPCstruct | MC16979

Metacluster Properties and Pfam Annotations

Number of structural domains701
Mean domain length (aa)88 ± 16 aa
Standard deviation of domain lengths15.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)17.62
Pfam Score90.47
Assigned Pfam label(s) PF20417- PF06365- PF20660- PF21166- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V1DJ60 409-489 None
A0A376B7F3 4-62 None
A0A1I8HP52 10-90 None
A0A5N5T2A4 445-526 None
A0A5N5T2T3 5-97 None
A0A816YB20 472-534 None
A0A2K6PX82 4-86 None
A0A1I8C0M3 12-96 None
T1KGA0 252-344 None
A0A2D6TPR1 36-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.