DPCstruct | MC16959

Metacluster Properties and Pfam Annotations

Number of structural domains9223
Mean domain length (aa)271 ± 60 aa
Standard deviation of domain lengths59.62
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.53
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.36
Mean intra-cluster local Distance Difference Test score0.38
Mean intra-cluster sequence similarity (%)12.67
Pfam Score82.67
Assigned Pfam label(s) PF14479- PF14484- CL0219- CL0010- CL0590

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4PR51 136-356 DAVQSLKQYREVLASVFDNDRHRAKLCLADFLDLDVGRHWQKSDSCLIMLSGRNENGVSSPMSWLSPMAVDMILSLLSEKSRVLFAM…
E6Q2R4 20-317 AGTVPPALVGRDADLEAIEDAIAQVAGGEPPQVALFVGERGMGKTVLLRRCEQMAREAGGIVLRGEMAPHADLQRAFAPGVQRAQED…
A0A7Y3JJC2 4-231 None
A0A6P8HJF2 91-432 None
A0A2V9TME3 53-284 None
A0A453DNV9 31-299 None
A0A453DYU8 21-330 None
A0A352AN12 468-805 None
A0A2G8LJ88 3-284 None
A0A2G8L1K1 172-458 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.