DPCstruct | MC16908

Metacluster Properties and Pfam Annotations

Number of structural domains399
Mean domain length (aa)217 ± 50 aa
Standard deviation of domain lengths50.43
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score88.62
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.58
Pfam Score95.27
Assigned Pfam label(s) CL0023- PF21771- PF02872- CL0163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A143HZG8 12-259 None
A0A6L8JQU5 208-471 None
A0A8B2NYT1 590-840 None
A0A8B2NS30 405-669 None
A0A1M4Z4M9 571-809 None
F5YEP3 317-589 None
A0A174QMJ4 33-229 None
A0A078B2S0 219-453 None
A7BME7 1-144 None
A0A2N4XMZ9 688-922 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.