DPCstruct | MC16903

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)218 ± 38 aa
Standard deviation of domain lengths37.90
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.89
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)16.27
Pfam Score60.71
Assigned Pfam label(s) PF20269- PF11902- PF20270

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A011NEG0 6-191 NHPQRFALNYELHARPPEALSIPEQASYLALATDPANRQAEYESIVELCTRYGVTAPAPEVNHFKVDLGTFRLKWERRAECSSYTFF…
A0A661CH41 3-209 KLIYLTLDLFLYDLREGLGQTEAEVTENRQNFQHKLLQTIDEQHFIQLDEHAFEPEYVELLGAQRHSDFESDIHEGYYYPVRLSDTY…
A0A7C6DPR9 9-189 None
A8L3R6 108-352 None
A0A1C0V6U4 10-252 None
A0A6M0ADX0 1-229 None
K0K976 3-223 None
A0A1H1Y8E9 1-186 None
A0A013VRS2 1-214 None
A0A1Y5YAA2 17-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.