DPCstruct | MC16882

Metacluster Properties and Pfam Annotations

Number of structural domains1862
Mean domain length (aa)108 ± 26 aa
Standard deviation of domain lengths25.62
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score72.09
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)27.03
Pfam Score99.57
Assigned Pfam label(s) PF02825- PF20979- PF18212- PF15842- PF00787

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A152A3G4 22-107 QFILKHRPTPPISEYHFKEMTEEIEVTKKNKERLGDCSICTVDFPLEDYVIKLPCKHYFHFDCITKWLGMHSVCPNCRFELPTEDS
A0A2G5EYV8 15-111 EFVHTVLCDVQAFNESFMDEEVDPILVPAAPSYVEALKTKQYDKENSKEESCSVCYQEFLMAEDVTLMPCSHIFHNNCIGRWLEMTN…
A0A061R066 48-191 None
A0A1V8SU11 421-544 None
A0A4Y7KSA3 156-253 None
A0A7S4PGU4 146-266 None
A0A7W1MB02 1-79 None
A0A3N4I9K1 415-494 None
A0A3N4IMD6 95-205 None
A0A6U0VJD2 66-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.