DPCstruct | MC1686

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)183 ± 27 aa
Standard deviation of domain lengths27.20
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score90.21
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)33.47
Pfam Score98.91
Assigned Pfam label(s) CL0023- CL0259

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A539E4Y0 2-111 LRHAVRINSLTELALTKLDVLDTFDTVKVCVGYSVDGRMLPHFPDRIELLAQVEPQYVSLPGWGRQLRSIRQVSELPAPAKAFVDLV…
A0A1F6AHE0 266-461 LGTLPDITASDTSSYGIHTGTAFWKVEDIEKRIGIFKIPYTSSVGVRRMPTHADDAWSKRVREKAHEYGTTTGRPRDILFLDIPMLS…
A0A7Y4QDL2 34-233 None
A0A2H0SPV5 29-228 None
A0A2K6SN73 198-394 None
A0A0J9V3A4 70-246 None
R1CKT9 4-133 None
A0A358XRE8 6-151 None
A0A2A2K597 148-319 None
A0A816QG99 135-360 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.