DPCstruct | MC16834

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)166 ± 10 aa
Standard deviation of domain lengths10.35
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score85.94
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)40.86
Pfam Score100.00
Assigned Pfam label(s) PF13236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8LF64 71-224 ENLGGSAGGMKFVWRGILFKLADGSRGPYLGNDEAAAKGAGHDLRGATHYLDARIRGLRYALQCLIDYKGFRMTAQAVLPVSSETLR…
L8GEL6 392-547 GEKYIVQGIFFKFALDIFGIYGGDEYAMKAASHDLKGLIHYYSCQIPGLHVPLMALIDYLGFRLIAITILPINNTTIQYGSCDAGQT…
A0A0S7F2W8 340-515 None
D7G5G9 306-460 None
A0A183J3F1 178-357 None
A0A6H5KFE7 1-175 None
A0A6V7YBR4 463-625 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.