DPCstruct | MC16810

Metacluster Properties and Pfam Annotations

Number of structural domains84
Mean domain length (aa)234 ± 60 aa
Standard deviation of domain lengths59.90
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score76.33
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)28.09
Pfam Score98.56
Assigned Pfam label(s) PF20235- PF03140- PF12274

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0Q3H8U4 55-311 SMPPVAGSTSRIISWEELAADREHDGDMDHKEEVASTMSLRRALLDKIHGYYLRALARLPAEYHRSMLHAGHCYGPMDPVSNIVLNT…
A0A0D3HAL7 9-170 RRVVRPQTRYRPLSVEQDDERSRLLSNIQSFYHHASARHTAAAICVGLLDPVSNILANTLLSDEVAPPVDDADLARRSLDGLVAFLL…
T1NNQ5 5-259 None
A0A0D9VNA6 25-289 None
A0A368Q8X6 63-268 None
A0A194YH41 368-573 None
A0A368PIJ3 176-347 None
A0A446IYQ8 55-309 None
A0A811MFP8 173-391 None
A0A3B6NNJ2 1-272 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.