DPCstruct | MC16728

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)87 ± 14 aa
Standard deviation of domain lengths13.71
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.33
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)53.15
Pfam Score94.59
Assigned Pfam label(s) CL0063- CL0115- CL0506

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7V7I0 15-93 YTSTRQNLKIGKNTKVLIQGFTGKQGTFHGQQMIEYGTNVVGGVSPSKAGTQHLGKPIFATAKEAKDATGADASVIYVP
A0A559MM86 11-103 LMQAAVRRQGYSTASAAYTSTAENLRITKDTKVIYQGFTGKQGSFHAEQAIAYGTQVVGGTNPKKAGQTHLGLPVFANVADAVRQAG…
A0A0B0IB99 1-86 None
A0A090S9Z3 1-73 None
A0A7C8PXK1 1-104 None
U6MZN9 61-171 None
A0A669BQL9 14-99 None
A0A401RP89 12-92 None
A0A2T3ACJ3 38-121 None
A0A535PPD3 1-77 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.