DPCstruct | MC16643

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)215 ± 30 aa
Standard deviation of domain lengths29.65
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.18
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.66
Pfam Score48.11
Assigned Pfam label(s) PF07196- PF02465- PF07195- PF00669

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A351CFN0 86-271 LFAANGSTNAGTLEYVLHSRDTEAGEYTVNITTAATQSTSTSNNGTVGENETLTIIDGDKVAEVVLTTDMTFSGIKNAINWEMSKVY…
A0A4Q2XMI1 37-299 NAGSGIDTGALVPALVTAQFAAKTAALTAKSTALTSQISGVSSLKSAITTFSSALDSLVKGGTLQTQPTSSDVSSISATAISGAKGS…
A0A7Y5VU33 1-203 None
A0A4Q2A1W5 1-222 None
A0A2U3L222 9-211 None
K6UMD5 447-602 None
A0A2E8S3X1 12-211 None
A0A661L5D0 3-200 None
A0A2H0PKZ1 24-225 None
A0A365VRC0 4-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.