DPCstruct | MC16642

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)206 ± 12 aa
Standard deviation of domain lengths11.88
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score81.06
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)47.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848I2A9 109-287 TIIMICPTRGFRNANDAAQAGSLGDLLRGREFEDILIAAQDHDLAVADAHAGALPLCRTMERLRHTRLLQRAQLRTWIARGLEVGQV…
A0A4Q2X4V1 1-198 MTIVTIDRLAGFVAGHQAPTTTVPIDATRADEIIAEASQGETLRTILAGREIDDILIAVQDDYLRIVDAFASALPLCGNMERTQNSL…
A0A2Z6AP27 13-230 None
A0A1W7M6K4 110-306 None
A0A1T5GLK0 210-431 None
S3FFL3 352-557 None
A0A7X4K7G4 137-350 None
A0A292ZMN1 1-206 None
A0A6A7BP63 225-437 None
A0A520FA05 174-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.