DPCstruct | MC16639

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)147 ± 30 aa
Standard deviation of domain lengths29.62
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score90.50
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)27.82
Pfam Score100.00
Assigned Pfam label(s) CL0497

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M5DYX2 29-151 HCLWFLKGTPVTAPLVDDYPQVQAWLGRVLGFGHGAPAEMSAEEALEVARGSQPAALPDESFSDPNGFLPGQAVAIAATDYGVDAVQ…
A0A818SVR9 26-153 HGLWFVMEVLGNEVEKILSQLNQPKLLAWFERVAKFGHGTRKEMTPEEALDVAKQTEPVEPTYIQNNSKSEWHVGQQLRVTPDDVGR…
Q2HGM0 59-184 None
A0A0F9XTC5 634-791 None
A0A370TQ04 168-328 None
A0A1V8SDH1 167-327 None
A0A418WFA3 1-78 None
A0A167DAZ1 125-306 None
A0A6A6Z6U0 540-685 None
F3L1B8 153-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.