DPCstruct | MC16603

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)87 ± 8 aa
Standard deviation of domain lengths8.25
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score75.60
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)70.22
Pfam Score100.00
Assigned Pfam label(s) CL0116

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446IWI3 94-170 LGAGEGAPLDLAALDGTWRLCYTSASDVLMLFEAAERLPLLQVGQIYQKFECKGRSDGGIVRNVVRWSIENLLEWSI
M8AY82 1-86 MEVSVEELGAGEGAPLDLAALDGTWRLCYTSASDVLMLFEAAERLPLLQVGQIYQKFECKGRSDGGIVRNVVRWSIENLLEVSQVI
A0A2U1N310 180-262 None
A9SJC5 66-153 None
A0A7J8M6G4 1-101 None
A0A1Z5S6U6 100-184 None
A0A452YLU3 40-116 None
A0A067H4F7 1-100 None
A0A452YLV6 39-115 None
A0A452YLV0 18-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.