DPCstruct | MC16588

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)91 ± 6 aa
Standard deviation of domain lengths5.89
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.80
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.93
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I1J879 25-116 RKSLVEEFDHLYVYNLRGNARTSGEQRRKEGGNAFEQGSRATVAIMLAVKDPAQQGDCVLHYRDIGDYLSREEKLEIVDASDVDTIE…
A0A6P0HX02 333-425 RKCLVDEFTSIYCFNLRGNQRTSGELSRKEGGKIFGSGSRATIAITLLIKNPGKKQESKLFYYDIGDYLSRGEKLNIIKHFGDISTI…
M5YGQ0 787-878 None
A0A7I9WDP9 35-118 None
A0A0M1J4B9 95-187 None
A0A6B0ZX10 448-535 None
A0A438P1E5 2-73 None
A0A4U8TPN2 871-971 None
A0A1J5QAS0 328-430 None
A0A838L135 150-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.