DPCstruct | MC16575

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)220 ± 29 aa
Standard deviation of domain lengths29.46
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.23
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)44.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B6LJC7 356-605 LYEVDAMDCPEYGCSRSSTLLEKLRPEFRLKHGINSFRDRHMWTINDMIKRKLPAEYSKRRSRQMDKWLCKLISSKPYFKHSDERQS…
A0A453NMA7 1-244 DEFQRYLPAYMEMLEQVDSMDVSDERDYLKEEALLQKLRPEFRSKYGINSCEHPYMLTISSLRQQQFYSMNGLIYQREKNKFLSKLI…
A0A0A9V157 1-183 None
A0A0A9U0I9 1-272 None
K3ZMF1 340-522 None
A0A368RTM5 730-966 None
A0A287M081 481-718 None
A0A811QJE7 634-851 None
M8ARF4 87-275 None
A0A453GCZ1 169-373 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.