DPCstruct | MC16568

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)133 ± 15 aa
Standard deviation of domain lengths15.06
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.67
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)28.55
Pfam Score60.95
Assigned Pfam label(s) PF06883- CL0410- PF04563- PF04567- PF04566

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
O28392 4-117 CRVYINGALVGFHDNGEELANKIRELRRKGRISNQVNVVYYPDSNEVRINTDAGRARRPLIVVKDGKPLVTPEHIEKIKKGELTIED…
A0A453NI65 1-129 EDLSLLSGEEIHAPGSFLVMFNGLILGKHRQPQRFANNMRTFRRSGKIGEFVSVFVNEKQHCIHIASDGGRVCRPLIIADKGRSRVK…
A0A6C0JBE8 467-559 None
A0A2A2KTH8 407-541 None
A0A1P8BFS9 523-658 None
A0A438DLU3 20-173 None
A0A1A9VXS4 2-149 None
A0A835Y177 602-735 None
A0A5E4QCT5 2-121 None
A0A6A2XBF3 697-842 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.