DPCstruct | MC16548

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)180 ± 15 aa
Standard deviation of domain lengths14.63
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score80.89
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)30.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F6UHX8 1-177 MTFTDMNDWIGSRYLREMAAIDNLSSVVRQCIEEGVQLEYELLLEQDEFIINHDAKVIRTPSPPPRPEPIETSQPDVFTIVQLGKLY…
X6NGR1 1-229 MSKLDEWIRLRIASEDEAIQSLILYVQDNIEQESPLYHRLLLNSDNVLIDNDLLLHPLPAPIKQSVQMEQELEGAFKISQLRKIQSS…
A0A7S4PBY1 296-470 None
T1FRF5 10-182 None
A0A498P2H4 609-781 None
A0A2G8L0A4 72-245 None
A0A7S4PCD6 69-238 None
A0A340XKH4 239-412 None
A0A7S1KTK4 885-1063 None
A0A653DPR4 414-582 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.