DPCstruct | MC16465

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)257 ± 33 aa
Standard deviation of domain lengths33.45
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score80.68
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)21.44
Pfam Score90.67
Assigned Pfam label(s) PF13874- PF18437- CL0647

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9B8Q8 2-200 PFLTGIDPRLWKQAQEDNPDRDRYVPVPIIGFGELCWRLRCQENETRLHQAFLDKVSDDITELQRRLATTKSKTAEYRRKFVELEHR…
A0A1Y3AUW2 33-269 IPDAQLRTNFNQPQCKQQLNQIFIDSFVDTIFTSLSKQEIEAYLSTPPKGIDERIWEQAKLENPDPQRFIPVPLIGFKALNHRFKLQ…
A0A182EJD3 265-500 None
A0A4Y7TFG6 2-233 None
G1Q069 1-243 None
A0A1V9ZK41 376-632 None
A0A7S3GL62 1-253 None
A0A4Y1QPY1 2-289 None
A2DR32 38-287 None
A0A2U1QB35 2-301 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.