DPCstruct | MC16445

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)125 ± 16 aa
Standard deviation of domain lengths16.04
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score80.44
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)34.43
Pfam Score66.67
Assigned Pfam label(s) CL0031- PF11127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X6K427 12-90 GAPGFAAAGGDVVRGAPRWDLERQVRLAAGTLVLTGLAAGRFVSPRLRVLAGAVGAGLSFSAATNICAMGKALARMPWN
A0A2T5AN93 4-136 PLLAEHGEEFASRLPGQVVLICQSGNRARQANERLEAVGADPDSVTVLDGGIAAFESAGGEVIRGKGVWAMDRQVRMAAGSLVLAGV…
A0A2D6TR87 42-166 None
A0A4Q2I049 2-115 None
A0A2M6X357 36-163 None
F8L3N9 43-174 None
A0A3D1F212 42-180 None
A0A1F9QHX4 28-162 None
A0A7V5UJW4 16-140 None
A0A1F7RUR7 266-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.