DPCstruct | MC1638

Metacluster Properties and Pfam Annotations

Number of structural domains141
Mean domain length (aa)191 ± 43 aa
Standard deviation of domain lengths43.03
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.63
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)42.37
Pfam Score99.20
Assigned Pfam label(s) CL0110- CL0020- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A268HZY1 25-157 KHLAAKYLLLAAFLGINLVYLIWRTAFTLPTVGILSLIVGILLLVTEWAGFLQSVVFTILSWKPFRRKTIPLSEFKELPTVDVYIAT…
A0A4D8Y1G3 17-213 MVINRVHALIHGAALAALFHYRITSITKSLPQLVIFAAELILSFQWLLSQGAKWNPVSRTACPDRLPADDKLPSVDVFVCTTDPVKE…
A0A0D3CLC4 110-280 None
A0A0E0I264 1-167 None
A0A6J5VVN7 186-419 None
A0A6V7PM05 2-183 None
A0A1U8PRH0 2-125 None
A0A5B6VWL8 31-201 None
A0A5B6VYT3 127-358 None
A0A446LX65 29-257 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.